Identification and characterisation of a multidrug resistance-related protein mRNA in the blue mussel Mytilus edulis

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Identification and characterisation of a multidrug resistance-related protein mRNA in the blue mussel Mytilus edulis

Membrane-associated transport proteins were discovered in the 1970s in mammals and were considered to be expressed in response to chemotherapy during cancer treatment. Prominent members of this class of proteins are multidrug resistance-related or -associated proteins (MRPs). Besides their expression in cancer cells, MRPs are ubiquitously expressed in normal tissues and are active transporters ...

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Identification and Antithrombotic Activity of Peptides from Blue Mussel (Mytilus edulis) Protein

The blue mussel (Mytilus edulis) reportedly contains many bioactive components of nutritional value. Water-, salt- and acid-soluble M. edulis protein fractions were obtained and the proteins were trypsinized. The resultant peptides were analyzed by ultra-performance liquid chromatography quadrupole time of flight tandem mass spectrometry (UPLC-Q-TOF-MS/MS). 387 unique peptides were identified t...

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Multi-xenobiotic resistance (MXR) transporters and biotransformation enzymes in the blue mussel Mytilus edulis

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Characterization of a glutathione S-transferase and a related glutathione-binding protein from gill of the blue mussel, Mytilus edulis.

The major isoenzyme of glutathione S-transferase (GST 1) was purified to homogeneity from cytosolic extracts of Mytilus edulis gill tissue by GSH-agarose affinity chromatography followed by Mono Q ion-exchange f.p.l.c. This enzyme was particularly active with 1-chloro-2,4-dinitrobenzene, ethacrynic acid and cumene hydroperoxide as substrates. Immunoblotting and amino acid sequencing studies ind...

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Mussel shells of Mytilus edulis as bioarchives

Introduction Conclusions References Tables Figures

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ژورنال

عنوان ژورنال: Marine Ecology Progress Series

سال: 2005

ISSN: 0171-8630,1616-1599

DOI: 10.3354/meps286167